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The antiapoptotic DeltaNp73 is degraded in a c-Jun–dependent manner upon genotoxic stress through the antizyme-mediated pathway

p73, the structural and functional homologue of p53, exists as two major forms: the transactivation-proficient, proapoptotic TAp73 or the transactivation-deficient, antiapoptotic DNp73. Expectedly, expression of both these major forms has to be coordinated precisely to achieve the desired cellular o...

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Detalhes bibliográficos
Main Authors: Dulloo, Iqbal, Gopalan, Ganesan, Melino, Gerry, Sabapathy, Kanaga
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841924/
https://ncbi.nlm.nih.gov/pubmed/20185758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906782107
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