The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo

To protect cells from oxidative DNA damage and mutagenesis, organisms possess multiple glycosylases to recognize the damaged bases and to initiate the Base Excision Repair pathway. Three DNA glycosylases have been identified in mammals that are homologous to the Escherichia coli Fpg and Nei proteins...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Liu, Minmin, Bandaru, Viswanath, Bond, Jeffrey P., Jaruga, Pawel, Zhao, Xiaobei, Christov, Plamen P., Burrows, Cynthia J., Rizzo, Carmelo J., Dizdaroglu, Miral, Wallace, Susan S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2010
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841873/
https://ncbi.nlm.nih.gov/pubmed/20185759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908307107
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