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Pain perception is altered by a nucleotide polymorphism in SCN9A

The gene SCN9A is responsible for three human pain disorders. Nonsense mutations cause a complete absence of pain, whereas activating mutations cause severe episodic pain in paroxysmal extreme pain disorder and primary erythermalgia. This led us to investigate whether single nucleotide polymorphisms...

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में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Reimann, Frank, Cox, James J., Belfer, Inna, Diatchenko, Luda, Zaykin, Dmitri V., McHale, Duncan P., Drenth, Joost P. H., Dai, Feng, Wheeler, Jerry, Sanders, Frances, Wood, Linda, Wu, Tian-Xia, Karppinen, Jaro, Nikolajsen, Lone, Männikkö, Minna, Max, Mitchell B., Kiselycznyk, Carly, Poddar, Minakshi, te Morsche, Rene H.M., Smith, Shad, Gibson, Dustin, Kelempisioti, Anthi, Maixner, William, Gribble, Fiona M., Woods, C. Geoffrey
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841869/
https://ncbi.nlm.nih.gov/pubmed/20212137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913181107
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