NKG2A inhibits iNKT cell activation in hepatic injury

Activation of invariant NKT (iNKT) cells in the liver is generally regarded as the critical step for concanavallin A (Con A)-induced hepatitis, and the role of NK cell receptors for iNKT cell activation is still controversial. Here we show that blockade of the NKG2A-mediated inhibitory signal with a...

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Autori principali: Kawamura, Toshihiko, Takeda, Kazuyoshi, Kaneda, Hiroshi, Matsumoto, Hiroaki, Hayakawa, Yoshihiro, Raulet, David H., Ikarashi, Yoshinori, Kronenberg, Mitchell, Yagita, Hideo, Kinoshita, Katsuyuki, Abo, Toru, Okumura, Ko, Smyth, Mark J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841747/
https://ncbi.nlm.nih.gov/pubmed/19109156
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