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Susceptibility to other antiherpes drugs of pathogenic variants of herpes simplex virus selected for resistance to acyclovir.

Cross-resistance data for a group of nine acyclovir-resistant variants of herpes simplex virus type 1 are reported. These mutants, which express either altered thymidine kinase (TK) or DNA polymerase, were all derived from the same wild-type (wt) strain after exposure to acyclovir in tissue culture....

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Bibliografische gegevens
Hoofdauteurs: Larder, B A, Darby, G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1986
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC284174/
https://ncbi.nlm.nih.gov/pubmed/3015009
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