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Susceptibility to other antiherpes drugs of pathogenic variants of herpes simplex virus selected for resistance to acyclovir.

Cross-resistance data for a group of nine acyclovir-resistant variants of herpes simplex virus type 1 are reported. These mutants, which express either altered thymidine kinase (TK) or DNA polymerase, were all derived from the same wild-type (wt) strain after exposure to acyclovir in tissue culture....

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Larder, B A, Darby, G
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1986
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284174/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3015009/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.5.894
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