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Enhanced Specific Delivery and Targeting of Oncolytic Sindbis Viral Vectors by Modulating Vascular Leakiness in Tumor

Genetic instability of cancer cells generates resistance after initial responses to chemotherapeutic agents. Several oncolytic viruses have been designed to exploit specific signatures of cancer cells, such as important surface markers or pivotal signaling pathways for selective replication. It is l...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tseng, Jen-Chieh, Granot, Tomer, DiGiacomo, Vincent, Levin, Brandi, Meruelo, Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841696/
https://ncbi.nlm.nih.gov/pubmed/19798121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2009.70
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