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Sindbis Viral Vectors Transiently Deliver Tumor-associated Antigens to Lymph Nodes and Elicit Diversified Antitumor CD8(+) T-cell Immunity

Tumors are theoretically capable of eliciting an antitumor immune response, but are often poorly immunogenic. Oncolytic viruses (OVs) have recently emerged as a promising strategy for the immunogenic delivery of tumor-associated antigens (TAAs) to cancer patients. However, safe and effective OV/TAA...

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Detalhes bibliográficos
Main Authors: Granot, Tomer, Yamanashi, Yoshihide, Meruelo, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978799/
https://ncbi.nlm.nih.gov/pubmed/24025748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.215
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