Interfering with multimerization of netrin-1 receptors triggers tumor cell death

Netrin-1 was recently proposed to control tumorigenesis by inhibiting apoptosis induced by the dependence receptors DCC (Deleted in colorectal cancer) and UNC5H. While a loss of these dependence receptors’ expression has been described as a selective advantage for tumor growth and progression in num...

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Hlavní autoři: Mille, Frédéric, Llambi, Fabien, Guix, Catherine, Delloye-Bourgeois, Céline, Guenebeaud, Céline, Castro-Obregon, Susana, Bredesen, Dale E., Thibert, Chantal, Mehlen, Patrick
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841642/
https://ncbi.nlm.nih.gov/pubmed/19543238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.75
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