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Mislocalization of mitochondria and compromised renal function and oxidative stress resistance in Drosophila SesB mutants
Mitochondria accumulate at sites of intense metabolic activity within cells, but the adaptive value of this placement is not clear. In Drosophila, sesB encodes the ubiquitous isoform of adenine nucleotide translocase (ANT, the mitochondrial inner membrane ATP/ADP exchanger); null alleles are lethal,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841493/ https://ncbi.nlm.nih.gov/pubmed/20009008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00147.2009 |
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