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Failure of topical acyclovir in ointment to penetrate human skin.

Topical acyclovir (ACV) in polyethylene glycol (PEG) ointment has been disappointing in the treatment of recurrent herpes simplex virus infections in immunocompetent patients. To investigate the possible role of poor drug delivery from this formulation, we studied the penetration of ACV through exci...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Freeman, D J, Sheth, N V, Spruance, S L
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1986
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284143/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3729337/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.5.730
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