Failure of topical acyclovir in ointment to penetrate human skin.

Topical acyclovir (ACV) in polyethylene glycol (PEG) ointment has been disappointing in the treatment of recurrent herpes simplex virus infections in immunocompetent patients. To investigate the possible role of poor drug delivery from this formulation, we studied the penetration of ACV through exci...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Freeman, D J, Sheth, N V, Spruance, S L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284143/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3729337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.29.5.730
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