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Sonic Hedgehog Is a Polarized Signal for Motor Neuron Regeneration in Adult Zebrafish

In contrast to mammals, the spinal cord of adult zebrafish has the capacity to reinitiate generation of motor neurons after a lesion. Here we show that genes involved in motor neuron development, i.e., the ventral morphogen sonic hedgehog a (shha), as well as the transcription factors nkx6.1 and pax...

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Detalhes bibliográficos
Main Authors: Reimer, Michell M., Kuscha, Veronika, Wyatt, Cameron, Sörensen, Inga, Frank, Rebecca E., Knüwer, Martin, Becker, Thomas, Becker, Catherina G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841428/
https://ncbi.nlm.nih.gov/pubmed/19955358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4748-09.2009
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