Analysis of the astray/robo2 Zebrafish Mutant Reveals that Degenerating Tracts Do Not Provide Strong Guidance Cues for Regenerating Optic Axons

During formation of the optic projection in astray/robo2 mutant zebrafish, optic axons exhibit rostrocaudal pathfinding errors, ectopic midline crossing and increased terminal arbor size. Here we show that these errors persist into adulthood, even when robo2 function is conditionally reduced only du...

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Main Authors: Wyatt, Cameron, Ebert, Anselm, Reimer, Michell M., Rasband, Kendall, Hardy, Melissa, Chien, Chi-Bin, Becker, Thomas, Becker, Catherina G.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058139/
https://ncbi.nlm.nih.gov/pubmed/20943924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3846-10.2010
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