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Replacing the wild type loxP site in BACs from the public domain with lox66 using a lox66 transposon
BACKGROUND: Chromatin adjoining the site of integration of a transgene affects expression and renders comparisons of closely related transgenes, such as those derived from a BAC deletion series retrofitted with enhancer-traps, unreliable. Gene targeting to a pre-determined site on the chromosome is...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841073/ https://ncbi.nlm.nih.gov/pubmed/20170521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-38 |
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