Development of Murine Lupus Involves the Combined Genetic Contribution of the SLAM and FcγR Intervals within the Nba2 Autoimmune Susceptibility Locus

Autoantibodies are of central importance in the pathogenesis of Ab-mediated autoimmune disorders. The murine lupus susceptibility locus Nba2 on chromosome 1 and the syntenic human locus are associated with a loss of immune tolerance that leads to antinuclear Ab production. To identify gene intervals...

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Detalhes bibliográficos
Main Authors: Jørgensen, Trine N., Alfaro, Jennifer, Enriquez, Hilda L., Jiang, Chao, Loo, William M., Atencio, Stephanie, Bupp, Melanie R. Gubbels, Mailloux, Christina M., Metzger, Troy, Flannery, Shannon, Rozzo, Stephen J., Kotzin, Brian L., Rosemblatt, Mario, Bono, María Rosa, Erickson, Loren D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841050/
https://ncbi.nlm.nih.gov/pubmed/20018631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901322
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