Roles of Arrest-Defective Protein 1(225) and Hypoxia-Inducible Factor 1α in Tumor Growth and Metastasis

BACKGROUND: Vascular endothelial growth factor A (VEGFA), a critical mediator of tumor angiogenesis, is a well-characterized target of hypoxia-inducible factor 1 (HIF-1). Murine arrest-defective protein 1A (mARD1A(225)) acetylates HIF-1α, triggering its degradation, and thus may play a role in decre...

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Autori principali: Lee, Mi-Ni, Lee, Shi-Nai, Kim, Se-Hee, Kim, Bora, Jung, Bo-Kyung, Seo, Ji Hae, Park, Ji-Hyeon, Choi, Jae-Hoon, Yim, Sun Hee, Lee, Mi-Ran, Park, Jong-Gil, Yoo, Ji-Young, Kim, Jeong Hun, Lee, Seung-Taek, Kim, Hwan-Mook, Ryeom, Sandra, Kim, Kyu-Won, Oh, Goo Taeg
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841038/
https://ncbi.nlm.nih.gov/pubmed/20194889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djq026
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