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Enhanced Inflow and Outflow Rates Despite Lower IOP in Bestrophin-2-Deficient Mice
PURPOSE: Bestrophin-2 (Best2), a putative Cl(−) channel is expressed in the nonpigmented epithelium (NPE). Disruption of Best2 in mice results in a diminished intraocular pressure (IOP). Aqueous humor dynamics were compared in Best2(+/+) and Best2(−/−) mice, to better understand the contribution of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840997/ https://ncbi.nlm.nih.gov/pubmed/18936135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2501 |
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