Partially Deglycosylated Equine LH Preferentially Activates β-Arrestin-Dependent Signaling at the Follicle-Stimulating Hormone Receptor

Deglycosylated FSH is known to trigger poor Gαs coupling while efficiently binding its receptor. In the present study, we tested the possibility that a deglycosylated equine LH (eLHdg) might be able to selectively activate β-arrestin-dependent signaling. We compared native eLH to an eLH derivative [...

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Main Authors: Wehbi, Vanessa, Tranchant, Thibaud, Durand, Guillaume, Musnier, Astrid, Decourtye, Jérémy, Piketty, Vincent, Butnev, Vladimir Y., Bousfield, George R., Crépieux, Pascale, Maurel, Marie-Christine, Reiter, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840809/
https://ncbi.nlm.nih.gov/pubmed/20107152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0347
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