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Inhibin-A Antagonizes TGFβ2 Signaling by Down-Regulating Cell Surface Expression of the TGFβ Coreceptor Betaglycan

Inhibin is an atypical member of the TGFβ family of signaling ligands and is classically understood to function via competitive antagonism of activin ligand binding. Inhibin-null (Inha−/−) mice develop both gonadal and adrenocortical tumors, the latter of which depend upon gonadectomy for initiation...

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Xehetasun bibliografikoak
Egile Nagusiak: Looyenga, Brendan D., Wiater, Ezra, Vale, Wylie, Hammer, Gary D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Endocrine Society 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840806/
https://ncbi.nlm.nih.gov/pubmed/20160125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0374
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