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Inhibin-A Antagonizes TGFβ2 Signaling by Down-Regulating Cell Surface Expression of the TGFβ Coreceptor Betaglycan

Inhibin is an atypical member of the TGFβ family of signaling ligands and is classically understood to function via competitive antagonism of activin ligand binding. Inhibin-null (Inha−/−) mice develop both gonadal and adrenocortical tumors, the latter of which depend upon gonadectomy for initiation...

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書誌詳細
主要な著者: Looyenga, Brendan D., Wiater, Ezra, Vale, Wylie, Hammer, Gary D.
フォーマット: Artigo
言語:Inglês
出版事項: The Endocrine Society 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840806/
https://ncbi.nlm.nih.gov/pubmed/20160125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0374
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