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Erythro-9-(2-hydroxy-3-nonyl) Adenine alone and in combination with 9-beta-D-arabinofuranosyladenine in treatment of systemic herpesvirus infections in mice.

Although the antiviral activity of erythro-9-(2-hydroxy-3-nonyl)adenine, a potent adenosine deaminase inhibitor, against herpes simplex virus type 1 in cell culture was readily confirmed, the compound was found to be totally ineffective in the treatment of experimentally induced systemic herpes simp...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Shannon, W M, Arnett, G, Schabel, F M, North, T W, Cohen, S S
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1980
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284056/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6255863/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.4.598
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