Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans

GNA2132 is a Neisseria meningitidis antigen of unknown function, discovered by reverse vaccinology, which has been shown to induce bactericidal antibodies in animal models. Here we show that this antigen induces protective immunity in humans and it is recognized by sera of patients after meningococc...

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Detalhes bibliográficos
Main Authors: Serruto, Davide, Spadafina, Tiziana, Ciucchi, Laura, Lewis, Lisa A., Ram, Sanjay, Tontini, Marta, Santini, Laura, Biolchi, Alessia, Seib, Kate L., Giuliani, Marzia M., Donnelly, John J., Berti, Francesco, Savino, Silvana, Scarselli, Maria, Costantino, Paolo, Kroll, J. Simon, O’Dwyer, Clíona, Qiu, Jiazhou, Plaut, Andrew G., Moxon, Richard, Rappuoli, Rino, Pizza, Mariagrazia, Aricò, Beatrice
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840514/
https://ncbi.nlm.nih.gov/pubmed/20133713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915162107
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