Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans

GNA2132 is a Neisseria meningitidis antigen of unknown function, discovered by reverse vaccinology, which has been shown to induce bactericidal antibodies in animal models. Here we show that this antigen induces protective immunity in humans and it is recognized by sera of patients after meningococc...

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Bibliografische gegevens
Hoofdauteurs: Serruto, Davide, Spadafina, Tiziana, Ciucchi, Laura, Lewis, Lisa A., Ram, Sanjay, Tontini, Marta, Santini, Laura, Biolchi, Alessia, Seib, Kate L., Giuliani, Marzia M., Donnelly, John J., Berti, Francesco, Savino, Silvana, Scarselli, Maria, Costantino, Paolo, Kroll, J. Simon, O’Dwyer, Clíona, Qiu, Jiazhou, Plaut, Andrew G., Moxon, Richard, Rappuoli, Rino, Pizza, Mariagrazia, Aricò, Beatrice
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2010
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840514/
https://ncbi.nlm.nih.gov/pubmed/20133713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915162107
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