Vaccination against Neisseria meningitidis Using Three Variants of the Lipoprotein GNA1870

Sepsis and meningitis caused by serogroup B meningococcus are devastating diseases of infants and young adults, which cannot yet be prevented by vaccination. By genome mining, we discovered GNA1870, a new surface-exposed lipoprotein of Neisseria meningitidis that induces high levels of bactericidal...

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Detalhes bibliográficos
Main Authors: Masignani, Vega, Comanducci, Maurizio, Giuliani, Marzia Monica, Bambini, Stefania, Adu-Bobie, Jeannette, Aricò, Beatrice, Brunelli, Brunella, Pieri, Alessandro, Santini, Laura, Savino, Silvana, Serruto, Davide, Litt, David, Kroll, Simon, Welsch, Jo Anne, Granoff, Dan M., Rappuoli, Rino, Pizza, Mariagrazia
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193853/
https://ncbi.nlm.nih.gov/pubmed/12642606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20021911
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