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COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis

Tumor growth depends on nutrients and oxygen supplied by the vasculature through angiogenesis. Here, we show that the chicken ovalbumin upstream promoter-transcription factor II (COUP-TFII), a member of the nuclear receptor family, is a major angiogenesis regulator within the tumor microenvironment....

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Autores principales: Qin, Jun, Chen, Xinpu, Xie, Xin, Tsai, Ming-Jer, Tsai, Sophia Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840495/
https://ncbi.nlm.nih.gov/pubmed/20133706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914619107
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