Uridylation of mature miRNAs and siRNAs by the MUT68 nucleotidyltransferase promotes their degradation in Chlamydomonas

Regulation of gene expression by small RNAs (∼20–30 nucleotides in length) plays an essential role in developmental pathways and defense responses against genomic parasites in eukaryotes. MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) commonly direct the inactivation of cognate sequences thr...

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Bibliografske podrobnosti
Main Authors: Ibrahim, Fadia, Rymarquis, Linda A., Kim, Eun-Jeong, Becker, James, Balassa, Eniko, Green, Pamela J., Cerutti, Heriberto
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840426/
https://ncbi.nlm.nih.gov/pubmed/20142471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912632107
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