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Uridylation of mature miRNAs and siRNAs by the MUT68 nucleotidyltransferase promotes their degradation in Chlamydomonas

Regulation of gene expression by small RNAs (∼20–30 nucleotides in length) plays an essential role in developmental pathways and defense responses against genomic parasites in eukaryotes. MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) commonly direct the inactivation of cognate sequences thr...

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Detalhes bibliográficos
Main Authors: Ibrahim, Fadia, Rymarquis, Linda A., Kim, Eun-Jeong, Becker, James, Balassa, Eniko, Green, Pamela J., Cerutti, Heriberto
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840426/
https://ncbi.nlm.nih.gov/pubmed/20142471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912632107
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