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Determining the distribution of probes between different subcellular locations through automated unmixing of subcellular patterns

Many proteins or other biological macromolecules are localized to more than one subcellular structure. The fraction of a protein in different cellular compartments is often measured by colocalization with organelle-specific fluorescent markers, requiring availability of fluorescent probes for each c...

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Autori principali: Peng, Tao, Bonamy, Ghislain M. C., Glory-Afshar, Estelle, Rines, Daniel R., Chanda, Sumit K., Murphy, Robert F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840343/
https://ncbi.nlm.nih.gov/pubmed/20133616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912090107
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