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LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling
Corepressors play an essential role in nuclear receptor-mediated transcriptional repression. In general, corepressors directly bind to nuclear receptors via CoRNR boxes (L/I-X-X-I/V-I) in the absence of ligand and appear to act as scaffolds to further recruit chromatin remodeling complexes to specif...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840334/ https://ncbi.nlm.nih.gov/pubmed/20133701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908656107 |
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