LIM protein Ajuba functions as a nuclear receptor corepressor and negatively regulates retinoic acid signaling

Corepressors play an essential role in nuclear receptor-mediated transcriptional repression. In general, corepressors directly bind to nuclear receptors via CoRNR boxes (L/I-X-X-I/V-I) in the absence of ligand and appear to act as scaffolds to further recruit chromatin remodeling complexes to specif...

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Autores principales: Hou, Zhaoyuan, Peng, Hongzhuang, White, David E., Negorev, Dmitri G., Maul, Gerd G., Feng, Yunfeng, Longmore, Gregory D., Waxman, Samuel, Zelent, Arthur, Rauscher, Frank J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840334/
https://ncbi.nlm.nih.gov/pubmed/20133701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908656107
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