Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d

Myeloid antigen-presenting cells (APC) express CD1d molecules that present exogenous and endogenous lipid antigens that activate CD1d-restricted T cells, natural killer T (NKT) cells. NKT cell activation has been shown to mediate the potent downstream activation of other immune cells through cell–ce...

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Bibliografiska uppgifter
Huvudupphovsmän: Muindi, Karen, Cernadas, Manuela, Watts, Gerald F. M., Royle, Louise, Neville, David C. A., Dwek, Raymond A., Besra, Gurdyal S., Rudd, Pauline M., Butters, Terry D., Brenner, Michael B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840327/
https://ncbi.nlm.nih.gov/pubmed/20133624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915056107
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