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Autophagy and the Ubiquitin-Proteasome System in Cardiac Dysfunction

The ubiquitin-proteasome system (UPS) and autophagy are two major intracellular protein degradation pathways. The UPS mediates the removal of soluble abnormal proteins as well as the targeted degradation of most normal proteins that are no longer needed. Autophagy is generally responsible for bulky...

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Bibliographic Details
Main Authors: Zheng, Qingwen, Wang, Xuejun
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840262/
https://ncbi.nlm.nih.gov/pubmed/20228723
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