Neutralization of Clostridium difficile toxin A using antibody combinations

The pathogenicity of Clostridium difficile (C. difficile) is mediated by the release of two toxins, A and B. Both toxins contain large clusters of repeats known as cell wall binding (CWB) domains responsible for binding epithelial cell surfaces. Several murine monoclonal antibodies were generated ag...

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Detalhes bibliográficos
Main Authors: Demarest, Stephen J, Hariharan, Mangala, Elia, Marikka, Salbato, Jared, Jin, Ping, Bird, Colin, Short, Jay M, Kimmel, Bruce E, Dudley, Michael, Woodnutt, Gary, Hansen, Geneviève
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2010
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840238/
https://ncbi.nlm.nih.gov/pubmed/20150758
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