Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts

Islet transplantation is a promising treatment for diabetes but long-term success is limited by progressive graft loss. Aggregates of the beta cell peptide islet amyloid polypeptide (IAPP) promote beta cell apoptosis and rapid amyloid formation occurs in transplanted islets. Porcine islets are an at...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Potter, K. J., Abedini, A., Marek, P., Klimek, A. M., Butterworth, S., Driscoll, M., Baker, R., Nilsson, M. R., Warnock, G. L., Oberholzer, J., Bertera, S., Trucco, M., Korbutt, G. S., Fraser, P. E., Raleigh, D. P., Verchere, C. B.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840144/
https://ncbi.nlm.nih.gov/pubmed/20160085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909024107
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki