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Pharmaceutical modulation of canonical Wnt signaling in multipotent stromal cells for improved osteoinductive therapy
Human mesenchymal stem cells (hMSCs) from bone marrow are regarded as putative osteoblast progenitors in vivo and differentiate into osteoblasts in vitro. Positive signaling by the canonical wingless (Wnt) pathway is critical for the differentiation of MSCs into osteoblasts. In contrast, activation...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840116/ https://ncbi.nlm.nih.gov/pubmed/20150512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914360107 |
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