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Stem cell-specific activation of an ancestral myc protooncogene with conserved basic functions in the early metazoan Hydra
The c-myc protooncogene encodes a transcription factor (Myc) with oncogenic potential. Myc and its dimerization partner Max are bHLH-Zip DNA binding proteins controlling fundamental cellular processes. Deregulation of c-myc leads to tumorigenesis and is a hallmark of many human cancers. We have iden...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840113/ https://ncbi.nlm.nih.gov/pubmed/20142507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911060107 |
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