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Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface
The recognition and binding of cholesterol is an important feature of many eukaryotic, viral, and prokaryotic proteins, but the molecular details of such interactions are understood only for a few proteins. The pore-forming cholesterol-dependent cytolysins (CDCs) contribute to the pathogenic mechani...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840085/ https://ncbi.nlm.nih.gov/pubmed/20145114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911581107 |
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