Macrophage Wnt7b is critical for kidney repair and regeneration

Macrophages are required for tissue homeostasis through their role in regulation of the immune response and the resolution of injury. Here we show, using the kidney as a model, that the Wnt pathway ligand Wnt7b is produced by macrophages to stimulate repair and regeneration. When macrophages are ind...

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Dettagli Bibliografici
Autori principali: Lin, Shuei-Liong, Li, Bing, Rao, Sujata, Yeo, Eun-Jin, Hudson, Thomas E., Nowlin, Brian T., Pei, Huaying, Chen, Lijun, Zheng, Jie J., Carroll, Thomas J., Pollard, Jeffrey W., McMahon, Andrew P., Lang, Richard A., Duffield, Jeremy S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840080/
https://ncbi.nlm.nih.gov/pubmed/20160075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912228107
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