Systemic antiangiogenic activity of cationic poly-L-lysine dendrimer delays tumor growth

This study describes the previously unreported intrinsic capacity of poly-L-lysine (PLL) sixth generation (G(6)) dendrimer molecules to exhibit systemic antiangiogenic activity that could lead to solid tumor growth arrest. The PLL-dendrimer-inhibited tubule formation of SVEC4-10 murine endothelial c...

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Autori principali: Al-Jamal, Khuloud T., Al-Jamal, Wafa’ T., Akerman, Simon, Podesta, Jennifer E., Yilmazer, Açelya, Turton, John A., Bianco, Alberto, Vargesson, Neil, Kanthou, Chryso, Florence, Alexander T., Tozer, Gillian M., Kostarelos, Kostas
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Physical Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840079/
https://ncbi.nlm.nih.gov/pubmed/20150514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908401107
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