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RNF8-dependent histone modifications regulate nucleosome removal during spermatogenesis

During spermatogenesis, global nucleosome removal occurs where histones are initially replaced by transition proteins and subsequently by protamines. This chromatin reorganization is thought to facilitate the compaction of the paternal genome into the sperm head and to protect the DNA from damaging...

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Autors principals: Lu, Lin-Yu, Wu, Jiaxue, Ye, Lin, Gavrilina, Galina B., Saunders, Thomas L., Yu, Xiaochun
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840054/
https://ncbi.nlm.nih.gov/pubmed/20153262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.01.010
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