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RNF8-dependent histone modifications regulate nucleosome removal during spermatogenesis

During spermatogenesis, global nucleosome removal occurs where histones are initially replaced by transition proteins and subsequently by protamines. This chromatin reorganization is thought to facilitate the compaction of the paternal genome into the sperm head and to protect the DNA from damaging...

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Hlavní autoři: Lu, Lin-Yu, Wu, Jiaxue, Ye, Lin, Gavrilina, Galina B., Saunders, Thomas L., Yu, Xiaochun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840054/
https://ncbi.nlm.nih.gov/pubmed/20153262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.01.010
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