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Complementary Actions of Inhibitors of Angiopoietin-2 and VEGF on Tumor Angiogenesis and Growth

Inhibition of angiopoietin-2 (Ang2) can slow tumor growth, but the underlying mechanism is not fully understood. Because Ang2 is expressed in growing blood vessels and promotes angiogenesis driven by vascular endothelial growth factor (VEGF), we asked whether the anti-tumor effect of Ang2 inhibition...

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Autors principals: Hashizume, Hiroya, Falcón, Beverly L., Kuroda, Takashi, Baluk, Peter, Coxon, Angela, Yu, Dongyin, Bready, James V., Oliner, Jonathan D., McDonald, Donald M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840050/
https://ncbi.nlm.nih.gov/pubmed/20197469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1977
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