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Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation

Cancer stem cells, which share many common properties and regulatory machineries with normal stem cells, have recently been proposed to be responsible for tumorigenesis and to contribute to cancer resistance1. The main challenges in cancer biology are to identify cancer stem cells and to define the...

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Detalhes bibliográficos
Principais autores: Guo, Wei, Lasky, Joseph L., Chang, Chun-Ju, Mosessian, Sherly, Lewis, Xiaoman, Xiao, Yun, Yeh, Jennifer E., Chen, James Y., Iruela-Arispe, M. Luisa, Varella-Garcia, Marileila, Wu, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840044/
https://ncbi.nlm.nih.gov/pubmed/18463637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06933
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