A Comparison Between Denaturing Gradient Gel Electrophoresis and Denaturing High Performance Liquid Chromatography in Detecting Mutations in Genes Associated with Hereditary Non-Polyposis Colorectal Cancer (HNPCC) and the Identification of 9 New Mutations Previously Unidentified by DGGE

Denaturing high performance liquid chromatography is a relatively new method by which heteroduplex structures formed during the PCR amplification of heterozygote samples can be rapidly identified. The use of this technology for mutation detection in hereditary non-polyposis colorectal cancer (HNPCC)...

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Bibliografiska uppgifter
Huvudupphovsmän: Meldrum, Cliff J, McPhillips, Mary, Crooks, Renee, Thomas, Lesley, Edkins, Ted, Creegan, Rohanna, Miller, Ewan, Agrez, Michael, Scott, Rodney J
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2003
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840012/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-1-1-39
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