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Deletion Mutations in an Australian Series of HNPCC Patients

Hereditary non polyposis colorectal cancer (HNPCC) is characterized by the presence of early onset colorectal cancer and other epithelial malignancies. The genetic basis of HNPCC is a deficiency in DNA mismatch repair, which manifests itself as DNA microsatellite instability in tumours. There are fo...

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Detalles Bibliográficos
Main Authors: McPhillips, Mary, Meldrum, Cliff J, Creegan, Rhona, Edkins, Edward, Scott, Rodney J
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837066/
https://ncbi.nlm.nih.gov/pubmed/20223028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-3-1-43
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