Comparative nephrotoxicities of high-dose netilmicin and tobramycin in rats.
The nephrotoxic potentials of netilmicin and tobramycin given in doses of 180 mg/kg per day for up to 14 days were compared in Fischer rats. At this dosage, tobramycin produced mortality and significant changes in renal structure and function; netilmicin evoked minimal nephrotoxicity.
Salvato in:
| Pubblicato in: | Antimicrob Agents Chemother |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1980
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283993/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7447411/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.18.2.346 |
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