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Baseline CSF p-tau levels independently predict progression of hippocampal atrophy in Alzheimer disease

OBJECTIVE: To investigate whether baseline CSF biomarkers are associated with hippocampal atrophy rate as a measure of disease progression in patients with Alzheimer disease (AD), patients with mild cognitive impairment (MCI), and controls, controlling for baseline neuropsychological and MRI finding...

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Détails bibliographiques
Auteurs principaux: Henneman, W J.P., Vrenken, H, Barnes, J, Sluimer, I C., Verwey, N A., Blankenstein, M A., Klein, M, Fox, N C., Scheltens, P, Barkhof, F, van der Flier, W M.
Format: Artigo
Langue:Inglês
Publié: American Academy of Neurology 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839552/
https://ncbi.nlm.nih.gov/pubmed/19770469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181b879ac
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