CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume

Abstract Introduction We examined the association between cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease, neural novelty responses, and brain volume in predementia old age. Methods We conducted a cross‐sectional analysis of the observational, multicentric DZNE‐Longitudinal Cognitiv...

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Autori principali: Emrah Düzel, David Berron, Hartmut Schütze, Arturo Cardenas‐Blanco, Coraline Metzger, Matthew Betts, Gabriel Ziegler, Yi Chen, Laura Dobisch, Daniel Bittner, Wenzel Glanz, Martin Reuter, Annika Spottke, Janna Rudolph, Frederic Brosseron, Katharina Buerger, Daniel Janowitz, Klaus Fliessbach, Michael Heneka, Christoph Laske, Martina Buchmann, Peter Nestor, Oliver Peters, Dominik Diesing, Siyao Li, Josef Priller, Eike Jakob Spruth, Slawek Altenstein, Alfredo Ramirez, Anja Schneider, Barbara Kofler, Oliver Speck, Stefan Teipel, Ingo Kilimann, Martin Dyrba, Jens Wiltfang, Claudia Bartels, Steffen Wolfsgruber, Michael Wagner, Frank Jessen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley 2018-01-01
Serie:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Soggetti:
Alzheimer's disease (AD)
Subjective cognitive decline (SCD)
Mild cognitive impairment (MCI)
Longitudinal
Cerebrospinal fluid (CSF)
Aβ42
Accesso online:https://doi.org/10.1016/j.dadm.2018.10.003
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