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Diastereoselective functionalisation of benzo-annulated bicyclic sultams: Application for the synthesis of cis-2,4-diarylpyrrolidines

The cis-dibromination of unsaturated bicyclic bridgehead sultams 5a and 5b, and experiments designed to understand the cis-stereochemical outcome of these reactions, are described. In the case of 5b, a novel solvent dependent carbocation rearrangement occurs with the formation of 18b. cis-Dibromides...

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Detalhes bibliográficos
Main Authors: Kelleher, Susan, Quesne, Pierre-Yves, Evans, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839534/
https://ncbi.nlm.nih.gov/pubmed/20300507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.5.69
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