Comparative Transduction Efficiency of AAV Vector Serotypes 1–6 in the Substantia Nigra and Striatum of the Primate Brain

Vectors derived from adeno-associated virus (AAV) are promising candidates for neural cell transduction in vivo because they are nonpathogenic and achieve long-term transduction in the central nervous system. AAV serotype 2 (AAV2) is the most widely used AAV vector in clinical trials based largely o...

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Bibliographic Details
Main Authors: Markakis, Eleni A, Vives, Kenneth P, Bober, Jeremy, Leichtle, Stefan, Leranth, Csaba, Beecham, Jeff, Elsworth, John D, Roth, Robert H, Samulski, R Jude, Redmond, D Eugene
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839442/
https://ncbi.nlm.nih.gov/pubmed/20010918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.286
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