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Intranodal Immunization With a Vaccinia Virus Encoding Multiple Antigenic Epitopes and Costimulatory Molecules in Metastatic Melanoma

Recombinant vaccinia virus (rVV) encoding tumor-associated antigens (TAAs) and adhesion or costimulatory molecules may represent important immunogenic reagents for cancer immunotherapy. Recently, intranodal (IN) antigen administration was suggested to be more immunogenic than intradermal (ID) vaccin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Adamina, Michel, Rosenthal, Rachel, Weber, Walter P, Frey, Daniel M, Viehl, Carsten T, Bolli, Martin, Huegli, Rolf W, Jacob, Augustinus L, Heberer, Michael, Oertli, Daniel, Marti, Walter, Spagnoli, Giulio C, Zajac, Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839441/
https://ncbi.nlm.nih.gov/pubmed/19935776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.275
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