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Culture of Melanoma Cells in 3-Dimensional Architectures Results in Impaired Immunorecognition by Cytotoxic T Lymphocytes Specific for Melan-A/MART-1 Tumor-Associated Antigen

OBJECTIVE: To assess the effects of the culture of melanoma cells in 3-dimensional (3D) architectures on their immunorecognition by cytotoxic T lymphocytes (CTLs) specific for tumor-associated antigens. SUMMARY BACKGROUND DATA: Growth in 3D architectures has been shown to promote the resistance of c...

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Bibliographic Details
Main Authors: Ghosh, Sourabh, Rosenthal, Rachel, Zajac, Paul, Weber, Walter P., Oertli, Daniel, Heberer, Michael, Martin, Ivan, Spagnoli, Giulio C., Reschner, Anca
Format: Artigo
Language:Inglês
Published: 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409875/
https://ncbi.nlm.nih.gov/pubmed/16327495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000189571.84213.b0
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